aTTP Treatment

The available treatments for aTTP include:

aTTP


1. Plasma exchange1
2. Immunosuppressants: Often administered as an adjunct to plasma exchange1
3. Cablivi (caplacizumab): A humanised bivalent nanobody consisting of two identical anti-von Willebrand factor building blocks. It works by preventing the ultra-large vWF-mediated platelet adhesion and the subsequent formulation and accumulation of microthrombi. To be used as an adjunct to plasma exchange and immunosuppression2

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References

1. Scully M, Hunt B, Benjamin S, et al. Br J Haematol. 2012;158:323–335.
2. Cablivi (caplacizumab). Summary of Product Characteristics.

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