aTTP Diagnosis

The diagnosis of aTTP should be treated as a medical emergency and a suspicion of aTTP should be raised in all cases of unexplained thrombocytopenia and anaemia.1


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Blood must be taken prior to initiation of first plasma exchange and treatment to assess baseline ADAMTS13 activity. A result of severely reduced ADAMTS13 activity helps to confirm a diagnosis of aTTP.1

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1. Scully M, Hunt B, Benjamin S, et al. Br J Haematol. 2012;158:323–335.
2. Veyradier A, Meyer D. J Thromb Haemost. 2005;3:2420–2427.

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