- Full blood count: anaemia and thrombocytopenia
- Blood ﬁlm: schistocyte fragments
- Reticulocyte count raised
- Heptoglobin reduced
- Lactate dehydrogenase raised due to haemolysis or organ damage
- Direct antiglobulin test negative
- Clotting screen, including ﬁbrinogen, normal
- Urea and electrolytes: renal impairment
1. Scully M, Hunt B, Benjamin S, et al. Br J Haematol. 2012;158:323–335.
2. Veyradier A, Meyer D. J Thromb Haemost. 2005;3:2420–2427.